IMHE OpenIR
Mortality-specific comorbidity among inpatients with ischemic stroke in West China
Si, Yang1,2,3; Xiao, Xiaoqiang1,2,3,4; Xiang, Shunju5; Guo, Jiang1,2,3; Yu, Nengwei1,2,3; Mo, Qiangning2,3,6; Guo, Fuqiang1,2,3; Sun, Hongbin1,2,3
Corresponding AuthorSi, Yang(sndxgl@163.com) ; Sun, Hongbin(shb1369@aliyun.com)
2019-08-01
Source PublicationACTA NEUROLOGICA SCANDINAVICA
ISSN0001-6314
Volume140Issue:2Pages:100-106
AbstractObjective This study aimed to investigate the current condition of mortality-specific comorbidity among hospitalized patients with ischemic stroke. Methods Five-year data of inpatients with ischemic stroke (IS) were extracted from the hospital medical database. A retrospective review of eighteen mortality-specific comorbidities in extensively validated Charlson Comorbidity Index (CCI) was carried out for each patient. In addition, the distribution of the CCI-based prognostic score was calculated. Results A total of 10 331 (male 57.6%) cases with IS were recruited in the present study. The most prevalent mortality-specific comorbidities from high to low were as follows: peripheral vascular disease (35.1%), diabetes uncomplicated (25.2%),mild liver disease (18.3%), chronic pulmonary disease (14.7%), congestive heart failure (10.8%), atrial fibrillation or flutter (10.3%), diabetes complicated (9.1%), moderate or severe renal disease (7.5%), and dementia (7.1%). High prevalence of comorbidities in the elderly was also noted (31.1% patients with score >= 3). Spearman correlation analysis with a rho of 0.25 (P < 0.001) showed a mild correlation between the age- and the CCI-based prognostic score. Conclusion High prevalence of peripheral vascular disease, diabetes, liver disease, chronic pulmonary disease, congestive heart failure, atrial fibrillation, or flutter as major contributors to mortality was presented in in-hospital patients with IS in our area. One-third of old patients with IS expose high mortality risk with the CCI score >= 3. Early prevention and management of the potential comorbidities are necessary to reduce the mortality.
Keywordcomorbidity ischemic stroke mortality outcome
DOI10.1111/ane.13108
Indexed BySCI
WOS KeywordRISK-FACTOR ; HEMORRHAGIC STROKE ; GLOBAL BURDEN ; INDEX ; PREDICTOR ; DEATH
Language英语
WOS Research AreaNeurosciences & Neurology
WOS SubjectClinical Neurology
WOS IDWOS:000474934000003
PublisherWILEY
Citation statistics
Document Type期刊论文
Identifierhttp://ir.imde.ac.cn/handle/131551/26678
Collection中国科学院水利部成都山地灾害与环境研究所
Corresponding AuthorSi, Yang; Sun, Hongbin
Affiliation1.Sichuan Acad Med Sci, Dept Neurol, Chengdu 610072, Sichuan, Peoples R China
2.Sichuan Prov Peoples Hosp, Chengdu 610072, Sichuan, Peoples R China
3.Chinese Acad Sci, Sichuan Translat Med Res Hosp, Chengdu, Sichuan, Peoples R China
4.Sichuan Acad Med Sci, Sichuan Prov Ctr Mental Hlth, Chengdu, Sichuan, Peoples R China
5.Sichuan Univ, West China Hosp, Dept Anesthesiol, Chengdu, Sichuan, Peoples R China
6.Sichuan Acad Med Sci, Dept Med Affair, Chengdu, Sichuan, Peoples R China
Recommended Citation
GB/T 7714
Si, Yang,Xiao, Xiaoqiang,Xiang, Shunju,et al. Mortality-specific comorbidity among inpatients with ischemic stroke in West China[J]. ACTA NEUROLOGICA SCANDINAVICA,2019,140(2):100-106.
APA Si, Yang.,Xiao, Xiaoqiang.,Xiang, Shunju.,Guo, Jiang.,Yu, Nengwei.,...&Sun, Hongbin.(2019).Mortality-specific comorbidity among inpatients with ischemic stroke in West China.ACTA NEUROLOGICA SCANDINAVICA,140(2),100-106.
MLA Si, Yang,et al."Mortality-specific comorbidity among inpatients with ischemic stroke in West China".ACTA NEUROLOGICA SCANDINAVICA 140.2(2019):100-106.
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